By Ong Yong Yau, Woo Keng Thye, Ng Han Seong, Patrick Tan, Tang Ong Teng
During this new version of A scientific method of drugs, the editor has assembled a panel of top clinicians and researchers, and reorganized the cloth within the key components of drugs, cardiology, endocrinology, gastroenterology, hematology, neurology, oncology, rheumatology, renal drugs and breathing medication. This booklet is exclusive -- it displays the adventure of prime specialists on styles of ailment within the Asia-Pacific zone. There are a number of different related books, yet these are via authors from the West and for that reason supply a distinct point of view. The publication additionally contains discussions on genetic illnesses, an infection and antimicrobial resistance to antibiotics, highlighting neighborhood incidences and records. every one bankruptcy begins with the elemental options of a selected subject and steadily develops the subject matter to provide the cutting-edge within the subject. With its specialize in practices certain to Asia-Pacific, this booklet is a needs to for the coed, working towards clinician and study scientist attracted to the most recent advancements during this a part of the realm.
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Extra resources for A Clinical Approach to Medicine
Silent myocardial ischemia Myocardial ischemia may also be asymptomatic. The adverse outcomes of patients with silent myocardial ischemia are increasingly recognized. Abnormal diastolic function may be the principal feature of coronary insufficiency. Instead of chest discomfort, these patients may present with effort-related dyspnea. Functional assessment of dyspnea is categorized into 4 grades of severity, similar to the classification used for angina. Orthopnea and paroxysmal nocturnal dyspnea (PND) are typical presentations of severe myocardial ischemia and denotes acute LV dysfunction.
Drug-induced causes must not be forgotten: Patients on glucocorticoid therapy or women on oral contraceptives are susceptible to iatrogenic hypertension. It is important to diagnose secondary hypertension because some of the causes may be potentially curable by operation or are amenable to specific therapeutic intervention. While it is not feasible to investigate every hypertensive patient for secondary causes, the clinician should select for further specialized testing, patients with features that suggest secondary hypertension (Table 5).
Recent observations indicate that it is not the severity of stenosis (plaque volume) that determines the outcome, but the type of stenosis (plaque composition) and the extent of collateral circulation. Therefore, there is a changing paradigm in viewing atherosclerosis more as an inflammatory disease than an anatomic disease. 7 0 High total cholesterol High LDLcholesterol Low HDLcholesterol Hypertension Smoking Diabetes mellitus Fig. 2 Prevalence of coronary risk factors among adults (aged 18 to 69 years) in Singapore.